منابع مشابه
Biomimetic Intrafibrillar Mineralization of Type I Collagen with Intermediate Precursors-loaded Mesoporous Carriers
Limited continuous replenishment of the mineralization medium is a restriction for in-situ solution-based remineralization of hypomineralized body tissues. Here, we report a process that generated amine-functionalized mesoporous silica nanoparticles for sustained release of biomimetic analog-stabilized amorphous calcium phosphate precursors. Both two-dimensional and three-dimensional collagen m...
متن کاملNanomechanics of Type I Collagen.
Type I collagen is the predominant collagen in mature tendons and ligaments, where it gives them their load-bearing mechanical properties. Fibrils of type I collagen are formed by the packing of polypeptide triple helices. Higher-order structures like fibril bundles and fibers are assembled from fibrils in the presence of other collagenous molecules and noncollagenous molecules. Curiously, howe...
متن کاملMultiphase intrafibrillar mineralization of collagen.
In the past, the two major biomineralization motifs, biosilicification and biocalcification, were considered as two discrete processes. However, there is increasing evidence of the existence of an inextricable relationship between biosilica and calcium-based biominerals. The recent discovery of a unique silica–chitin–aragonite biocomposite in one genus of demosponges (Verongida) introduces a no...
متن کاملPurification of Type I Soluble Collagen
Objective-To study collagenase production in labial salivary glands in patients with Sjogren's syndrome (SS). Methods-Collagenases were localised in labial salivary glands by immunohistochemistry. Collagenase activity against triple helical type I collagen monomers in stimulated saliva was measured using sodium dodecyl sulphate polyacrylamide gel electrophoresis and laser densitometry; tissue i...
متن کاملAnalysis of Type I Collagen Products
Advanced BioMatrix offers a large number of extracellular matrix (ECM) and three dimensional (3D) scaffold products with one of the most extensive Type I collagen product offerings (see Exhibit 1). One analytical method for evaluating the quality, purity and consistency of the products is Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis (SDS PAGE electrophoresis). The purpose of the do...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2003
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(03)74466-x